Musculoskeletal Health of 40-65 Year Old Males and Females in Kosova and the Impact of N05B, A02B (PPI, H2RA), H02AB and Lifestyle Factors on It

Autor(en)

Ermira Krasniqi, Mynyr Koni, Harald Tschan, Blerim Krasniqi, Antigona Kabashi, Arben Boshnjaku

Abstrakt

BACKGROUND: This observational, cross-sectional study investigates the impact of medication usage, physical activity (PA) and nutritional status on musculoskeletal health (MSH) in males and females aged 40-65 in the population of a post conflict, developing country.

METHODS: Bone Mineral Density (BMD), T-score and Z-score at distal forearm regions (measured by DEXA scan), together with isometric hand grip strength (dynamometer) were evaluated in a total of 162 subjects (53 Males, average age 55.15±7.12 and 109 Females, 54.27±5.1). Additionally, bio-anthropometric assessments, medication usage, PA level and nutritional status were assessed.

RESULTS: Significant differences (p<0.05) were found in total subjects Body Mass Index (BMI), PA, BMD, T-score and Hand grip between genders. 42% of total participants met the diagnostic criteria of, out of which 6.8% with T-score below -2, while no cases of Osteoporosis was recorded. N05B Anxiolytics and A02B Drugs for peptic ulcer and gastro-oesophageal reflux disease medication groups consumption turned to have no significant differences (p>0.05) in BMD, T-score, and hand grip in total population, except for A02B where p<0.05 were found in Hand grip, as well as between female consumers and no consumers in all variables. Meanwhile, in total subjects consuming H02AB Glucocorticoids p<0.05 were observed in BMD and T-score, but not on hand grip.

CONCLUSIONS: This study shows a low risk for MSH problems amongst the studied population in Kosova, while the consumption of H02AB medication group in both genders and A02B in females only for extended periods might effect MSH, therefore appropriate benefit/risk assessment should be made before prescribing these medications, notwithstanding age, gender, PA or nutritional status.

Organisation(en)

Institut für Sport- und Bewegungswissenschaft

Externe Organisation(en)

University of Medicine, Tirana, University of Tirana, College of Medical Sciences "Rezonanca"

Journal

Medical Archives

Band

Seiten

359 - 363

Anzahl der Seiten

ISSN

0350-199X

DOI

https://doi.org/10.5455/medarh.2016.70.359-363

Publikationsdatum

10-2016

Peer-reviewed

ÖFOS 2012

303028 Sportwissenschaft

Schlagwörter

ASJC Scopus Sachgebiete

Allgemeine Medizin

Link zum Portal

https://ucrisportal.univie.ac.at/de/publications/95e79104-b2a4-45ba-b334-e9bfb2020d48