Adrenal disorders
- Autor(en)
- Alois Gessl, Rosa Lemmens, Alexandra Kautzky-Willer
- Abstrakt
The most frequent cause nowadays is autoimmune adrenalitis, which can be confirmed by the presence of 21-hydroxylase-antibodies (Oelkers 1996). When suspected on clinical grounds, adrenal insufficiency has to be confirmed by inappropriately low serum cortisol with elevated adrenocorticotropin (ACTH) (in case of primary adrenal insufficiency). A morning plasma cortisol =3 µg/dl is indicative for adrenal failure, whereas a cortisol =19 µg/dl rules out the disorder (Grinspoon and Biller 1994) if corticosterone-binding globulin (CBG) is normal. All other patients need dynamic testing (short ACTH stimulation test). A low ACTH in the presence of low cortisol points to secondary adrenal failure, in which case ACTH stimulation might be less reliable, especially when of recent onset.
- Organisation(en)
- Externe Organisation(en)
- Medizinische Universität Wien
- Seiten
- 341-359
- Anzahl der Seiten
- 19
- DOI
- https://doi.org/10.1007/978-3-642-30726-3_16
- Publikationsdatum
- 2012
- Peer-reviewed
- Ja
- ÖFOS 2012
- 301206 Pharmakologie, 302012 Diabetologie
- Sustainable Development Goals
- SDG 3 – Gesundheit und Wohlergehen
- Link zum Portal
- https://ucrisportal.univie.ac.at/de/publications/665a5c00-9dd6-4d68-92e8-d7d629e4a767