Factors Influencing Clinical Trials of Herbal Medicinal Products - Using Ginger as Example

Autor(en)
Ingrid Hook, Liselotte Krenn, Barbara Steinhoff, Evelyn Wolfram
Abstrakt

Ginger (Zingiber officinale) has a global use as a spice, an ingredient of beverages, food supplements (syn. dietary supplements), as well as herbal medicinal products. Since the last update of ginger in ESCOP Monographs in 2009 a significant number of papers concerning its bioactive constituents and clinical uses have been published. From this large number and selecting those references (almost 500) considered most relevant to clinical aspects and therapeutic indications, the following issues are considered to be potentially important to research on other medicinal plants: [i] quality assessment; [ii] pre-clinical (in vivo) studies; [iii] quality of clinical trials; [iv] ethnicity of clinical trial participants and [v] effects of sex-gender on activity and therapeutic indications.

Organisation(en)
Department für Pharmazeutische Wissenschaften
Externe Organisation(en)
Trinity College Dublin, European Scientific Cooperative on Phytotherapy, Zürcher Hochschule für Angewandte Wissenschaften (ZHAW)
Journal
Planta Medica: natural products and medicinal plant research
Band
91
Seiten
880-890
Anzahl der Seiten
11
ISSN
0032-0943
DOI
https://doi.org/10.1055/a-2686-6315
Publikationsdatum
09-2025
Peer-reviewed
Ja
ÖFOS 2012
301212 Klinische Pharmazie
Schlagwörter
ASJC Scopus Sachgebiete
Analytical Chemistry, Molecular Medicine, Pharmacology, Pharmaceutical Science, Drug Discovery, Complementary and alternative medicine, Organic Chemistry
Link zum Portal
https://ucrisportal.univie.ac.at/de/publications/9cfce384-8302-4ad9-91ac-366326937744